ncRNA name | miR(5,B,7) |
ncRNA Category | miRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | RPE/choroidal flat‐mounts |
Methods | subretinal injection, immunostaining, Western blot, histological analysis |
Expression pattern | associated |
Functional description | LV-delivered microRNAs targeting the Vegfa gene in RPE cells reduced the size of laser-induced CNV in mice 28 days PI, as a consequence of diminished VEGF levels. |
PubMed ID | 28750559 |
Year | 2017 |
Title | Suppression of choroidal neovascularization in mice by subretinal delivery of multigenic lentiviral vectors encoding anti-angiogenic microRNAs. |
Drug-related ncRNA | NO |
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